Co2 total assay
| Product | Method | Size | Catalog | Price | Quantity |
| Co2 total assay | 376nm | R1 6x50ml | CD7942 | £132.00 | |
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- Format
Lyophilised - Assay Range
3.82 - 50mmol/l - Working Stability 15-25 °C
40 hours - Working Stability 2-8 °C
70 hours - Material Safety Data Sheets
Intended Use
For the quantitative in vitro determination of CO2 in serum and plasma. This product is suitable for use on the Hitachi 704, 902, 911 and 912.
Clinical Significance
Carbon dioxide (CO2) is a metabolic waste product of cellular respiration.
CO2 (bicarbonate) levels are usually tested alongside other electrolytes including sodium, potassium and chloride. Measurements can be used to detect and monitor electrolyte imbalances within the body.
Increased levels of blood CO2 (hypercapnia) may indicate problems removing CO2 and can result in respiratory acidosis. CO2 levels rise with decreased alveolar ventilation due to diseases of the lungs, bronchial tree, or breathing CO2 enriched air. Levels are regulated by the kidneys with extremely high levels indicating difficulty regulating pH. Increased levels are associated with emphysema, Cushing’s syndrome, Conn’s syndrome and metabolic acidosis. Depression of the overall lung capacity by certain drugs may also lead to retention of CO2.
Low levels of CO2 (hypocapnia) are associated with respiratory alkalosis, metabolic acidosis, Addison’s disease, shock, kidney failure, diabetic ketoacidosis, in cases of aspirin overdose and starvation.
Principle
The reduction in absorbance at 376 nm caused by the oxidation of NADH is proportional to the bicarbonate concentration in the sample.
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