Gamma gt (liquid) (mono reagent) assay
| Product | Method | Size | Catalog | Price | Quantity |
| Gamma gt (liquid) (mono reagent) assay | Carboxy (1 shot) | 6 x 20.5 | GT3874 | £89.25 | |
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- Format
Liquid - Assay Range
3.9 - 1397 U/L - Working Stability 15-25 °C
_ - Working Stability 2-8 °C
Stable to expiry - Material Safety Data Sheets
Intended Use
For the quantitative in vitro determination of L-γ-Glutamyltransferase (γ-GT) activity in serum and plasma. This product is suitable for use on the RX Series instruments which includes the Rx Daytona and the Rx Imola.
Clinical Significance
Gamma-glutamyl transferase (γ-GT) in the serum originates primarily from the hepatobiliary system. Therefore γ-GT is elevated in all forms of liver disease and has been shown to be more sensitive than alkaline phosphatase in detecting obstructive jaundice, cholangitis and cholecystitis. High levels of γ-GT are also seen in patients with primary or secondary liver cancer. Increased levels are also observed in cases of alcohol abuse and in alcoholic liver cirrhosis.
In patients receiving anticonvulsant drugs such as Phenytoin and Phenobarbital, increased levels of the enzyme in serum may reflect induction of new enzyme activity and the toxic effects of alcohol and other drugs on the microsomal structures in liver cells. Although γ -GT is the most sensitive enzymatic indicator of hepatobiliary disease it can not be used to differentiate between different types of hepatobiliary disease. γ -GT however can be used in combination with other biochemical markers to discriminate between different types of hepatobiliary disease.
Principle
This is an optimized standard method according to the European Committee for Clinical Laboratory standards (ECCLS).
- RX dedicated
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