Gamma gt assay
| Product | Method | Size | Catalog | Price | Quantity |
| Gamma gt assay | Carboxy (1 shot) | 6 x 50ml | GT7957 | £187.00 | |
| Shipping costs will be added at the checkout stage, click here for charges. | |||||
- Format
Liquid - Assay Range
13 - 1265U/L - Working Stability 15-25 °C
5 days - Working Stability 2-8 °C
21 days - Material Safety Data Sheets
Intended Use
For the quantitative in vitro determination of γ-glutamyl transferase (γ-GT) in serum or plasma. This product is suitable for use on the Hitachi 704, 717, 902 and 911/912.
Clinical Significance
Gamma-glutamyl transferase (γ-GT) in the serum originates primarily from the hepatobiliary system. Therefore γ-GT is elevated in all forms of liver disease and has been shown to be more sensitive than alkaline phosphatase in detecting obstructive jaundice, cholangitis and cholecystitis. High levels of γ-GT are also seen in patients with primary or secondary liver cancer. Increased levels are also observed in cases of alcohol abuse and in alcoholic liver cirrhosis.
In patients receiving anticonvulsant drugs such as Phenytoin and Phenobarbital, increased levels of the enzyme in serum may reflect induction of new enzyme activity and the toxic effects of alcohol and other drugs on the microsomal structures in liver cells. Although γ -GT is the most sensitive enzymatic indicator of hepatobiliary disease it can not be used to differentiate between different types of hepatobiliary disease. γ -GT however can be used in combination with other biochemical markers to discriminate between different types of hepatobiliary disease.
Principle
Colorimetric method. The substrate L-γ -glutamyl-3-carboxy-4-nitroanilide, in the presence of glycylglycine is converted by γ -GT in the sample to 5-amino-2-nitrobenzoate which can be measured at 405nm.
- Hitachi dedicated
Related Products
We accept all major credit cards
You can also buy via phone or email
+44 (0) 9442 2413
marketing@randox.com
