Magnesium (liquid) assay
| Product | Method | Size | Catalog | Price | Quantity |
| Magnesium (liquid) assay | Xylidyl Blue | 3 x 100ml | MG531 | £84.25 | |
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- Format
Liquid ready to use - Assay Range
0.036 - 2.34mmol/l - Working Stability 15-25 °C
_ - Working Stability 2-8 °C
Stable to expiry - Material Safety Data Sheets
Intended Use
For the quantitative in vitro determination of Magnesium in serum, plasma and urine. This product is suitable for both manual and automated use.
Clinical significance
Magnesium is one of the major intracellular cations in the body; its action is closely related to that of calcium.
Magnesium deficiency, hypomagnesaemia can result in various neuromuscular disorders, weakness, tremors, tetany and convulsions. Low levels in the blood are often associated with hypocalcaeia, intravenous therapy, diabetes mellitus, gastrointestinal disorders such as Crohn’s disease, hypoparathyroidism, alcoholism, dialysis and pregnancy.
Increased serum magnesium levels are associated with dehydration, severe diabetic acidosis, Addison's disease, hypothyroidism and hyperparathyroidism. Conditions that interfere with the glomerular filtration as in renal failure result in retention of magnesium and hence elevation of serum levels.
Principle
Magnesium ions react with xylidyl blue in an alkaline medium to form a water soluble purple-red chelate, the colour intensity of which is proportional to the concentration of magnesium in the sample. Calcium is excluded from the reaction by complexing with EGTA.
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