Transthyretin (prealbumin) (liquid) assay
| Product | Method | Size | Catalog | Price | Quantity |
| Transthyretin (prealbumin) (liquid) assay | Immunoturbidimetric | R1 6 x 20ml, R2 3 x 11ml | PA3843 | £830.80 | |
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- Format
Liquid ready to use - Assay Range
2.3 - 65mg/dl - Working Stability 15-25 °C
_ - Working Stability 2-8 °C
28 days - Material Safety Data Sheets
Intended Use
For the quantitative in vitro determination of prealbumin (transthyretin) in serum. This product is suitable for use on the RX Series instruments which includes the Rx Daytona and Rx Imola.
Clinical Significance
Prealbumin (transthyretin) is a tryptophan-rich 55KDa protein synthesized in liver hepatocytes and functions primarily as a binding and transport protein. The small body pool, short half-life and easy quantification on existing laboratory equipment make prealbumin the preferred marker of visceral protein status.
Prealbumin levels in the serum are most often used to assess the nutritional status of individuals undergoing surgery, those receiving parenteral nutrition, those who have been ill for a long period of time and hospitalized patients.
Low levels of prealbumin indicate malnutrition and may be seen in patients with hyperthyroidism, liver disease and cancer. Higher than normal levels of prealbumin are associated with Hodgkin’s disease, high doses of anti-inflammatory drugs and hyperactive adrenal glands.
Principle
Neat sample is incubated with assay buffer before the addition of antibody reagent, specific for human prealbumin. The absorbance of the resulting turbid solution is read at 340 nm and is proportional to the concentration of prealbumin in the sample. By constructing a standard curve from the absorbance of known standards, the actual concentration of prealbumin in the sample can be determined.
- Various
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