Urea assay
| Product | Method | Size | Catalog | Price | Quantity |
| Urea assay | Modified Berthelot | 5 x 100ml | UR107 | £78.50 | |
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- Format
Liquid - Assay Range
Linear up to 33.3mmol/l - Working Stability 15-25 °C
_ - Working Stability 2-8 °C
1 month - Material Safety Data Sheets
Intended use
For the quantitative in vitro determination of Urea in serum, plasma and urine. This product is suitable for Manual use.
Clinical Significance
Urea is synthesized in the liver and is a waste product of protein digestion removed from the body in the urine. Urea is measured to monitor patients undergoing dialysis and to evaluate renal and metabolic function.
Higher than normal levels of urea indicate problems with kidney function however levels are also increased as a result of congestive heart failure, heart attack, shock and dehydration. Lower than normal levels are not usually of clinical significance however have been associated with pregnancy and liver disease.
Principle
The method is based on the following reaction:-
urease
Urea + H2O ---> 2NH3 + CO2
Salicylate and hypochlorite in the reagent react with the ammonium ions to form a green complex (2.2 dicarboxylindophenol).
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