Syphilis (rpr) assay
| Product | Method | Size | Catalog | Price | Quantity |
| Syphilis (rpr) assay | Card Test | 500T | SY1479 | £172.75 | |
| Shipping costs will be added at the checkout stage, click here for charges. | |||||
- Material Safety Data Sheets
Intended Use
For the quantitative in vitro determination of Syphilis in serum and plasma. This product is suitable for Manual use.
Clinical Significance
Syphilis is a chronic, contagious and often congenital venereal disease caused by Treponema pallidum. This organism belongs to a gram-negative group of bacteria called the Spirochetes, which are defined by their unique cellular structure. Infection results from contact with moist surfaces, originating in lesions of the epithelial tissue of the skin and mucous membranes. If untreated the disease may result in irreversible changes in the cardiovascular and nervous system. Syphilis remains a disease of high incidence, despite advances in modern antibiotic therapy.
Principle
The Syphilis RPR test is a macroscopic non-treponemal flocculation test for the detection and titration of reagins (circulating antibodies produced as a result of the tissue damage caused by the disease) in serum or plasma. The antigen employed in the kit is a modification of the VDRL antigen. It consists of a colloidal suspension of cardiolipin balanced with lecithin and cholesterol, mixed with microparticulate carbon. In the presence of reagins agglutination occurs which is visibly enhanced by the presence of the microparticulate carbon.
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