Home Reagents Antioxidants Reagents Albumin (liquid) assay
Quality Guranteed Fast Delivery ad for support

Albumin (liquid) assay

Product Method Size Catalog Price Quantity
Albumin (liquid) assay BCG (RX dedicated) 9 x 51ml AB3800 $76.05
Shipping costs will be added at the checkout stage, click here for charges.
  • Format
    Liquid ready to use
  • Assay Range
    3.20 - 50.6 g/L
  • Working Stability 15-25 °C
    Stable to expiry
  • Working Stability 2-8 °C
    _
Request Kit Insert

Intended Use

For the quantitative in vitro determination of albumin in serum and plasma. This product is suitable for use on RX Monza instruments including the Rx Daytona and the Rx Imola and utilizes the bromocresol green method.


Clinical Significance


Albumin is the most abundant serum protein representing 55-65% of the total protein. It is synthesized in the liver and has a half-life of 2 to 3 weeks. The main biological functions of albumin are to maintain the water balance in serum and plasma and to transport and store a wide variety of ligands e.g. fatty acids, calcium, bilirubin and hormones such as thyroxine.

Low levels of albumin in the blood are associated with a variety of diseases. Hypoalbuminemia (low albumin levels) has been implicated in the following conditions: impaired albumin synthesize in the liver; liver disease; kidney disease; malnutrition or malabsorption; generalized shock; inflammation; burns; dermatitis; intestinal disease and Crohns disease. Hyperalbuminemia (high albumin levels) has little diagnostic relevance except, perhaps in dehydration.

Some diabetic patients present with complications, such as kidney failure or anemia, so we at Randox have developed innovative tests that allow the accurate measurement of blood glucose, through secondary markers that are not influenced by such complications. Albumin is a protein with a high binding affinity to glucose. Glycated Albumin (GA) is a glycemic control marker for diabetes mellitus, reflecting the blood glucose status at 2 to 4 weeks, so is more rapid than HbA1c, which is optimal if measured at 6 to 8 weeks. Albumin measurement allows:

  • Faster confirmation of results following diet, exercise or medication
  • Permits timely adjustment of medication
  • Applicable to gestational diabetic patients and diabetic patients with unstable blood glucose levels where HbA1c is not effective
  • Suitable for use when HbA1c values are adversely impacted by shortened life spans of red blood cell such is the case in diabetic nephropathy and anemia. In these cases, HbA1c does not accurately reflect blood glucose status and it has been proven that Glycated albumin gives a more useful check for blood glucose control


Principle

The measurement of serum albumin is based on its quantitative binding to the indicator 3,3',5,5'­tetrabromo­m cresol sulphonphthalein (bromocresol green). The albumin­BCG­complex absorbs maximally at 578 nm.

Available Applications

  • Abbott Architect + Aeroset
  • Alcyon 300 + Falcor
  • ATAC 8000
  • BS-200, BS-300
  • BT2000/BT3000/ILAB300/TARGA
  • Clinline, Lisa Series + Mascott Plus
  • Cobas Mira, Mira S + Mira Plus
  • Express 550
  • Hitachi 704,717,747,902,904, 911,912,917
  • ILAB 600
  • Konelab 20i, 30i + 60i
  • Olympus AU 400/600/ AU2700
  • Prestige
  • RA100/XT/Opera
  • Saba Autolab
  • Synchron CX4, 5, 7, 9 + LX20, Unicel 600/800
  • Vitalab Flexor, Selectra E + Selectra II