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Albumin assay

Product Method Size Catalog Price Quantity
Albumin assay BCG 6 x 100ml AB362 $65.69
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  • Format
    Concentrate
  • Assay Range
    0.287 - 7.55 g/L
  • Working Stability 15-25 °C
    3 months
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Intended Use

For the quantitative in vitro determination of albumin in serum and plasma. This product is suitable for Manual use and on the Rx Monza analyser.

Clinical Significance

Albumin is the most abundant serum protein representing 55-65% of the total protein. It is synthesised in the liver and has a half-life of 2 to 3 weeks.

The main biological functions of albumin are to maintain the water balance in serum and plasma and to transport and store a wide variety of ligands e.g. fatty acids, calcium, bilirubin and hormones such as thyroxine. Albumin also provides an endogenous source of amino acids. Hypoalbuminaemia is associated with the following conditions: analbuminaemia; impaired albumin synthesis in the liver; liver disease; malnutrition or malabsorption; generalised shock; burns or dermatitis; kidney disease and intestinal disease. Hyperalbuminaemia has little diagnostic relevance except, perhaps in dehydration.

Principle

The measurement of serum albumin is based on its quantitative binding to the indicator 3,3',5,5'-tetrabromo-m cresol sulphonephthalein (bromocresol green, BCG). The albumin-BCG-complex absorbs maximally at 578 nm , the absorbance being directly proportional to the concentration of albumin in the sample.

Available Applications

RX Monza