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Alanine Aminotransferase (ALT) assay (manual)

Product Method Size Catalog Price Quantity
Alanine Aminotransferase (ALT) assay (manual) Colorimetric 2 x 100ml AL100 $50.98
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  • Format
    Liquid ready-to-use
  • Working Stability 2-8 °C
    Stable to expiry
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Intended Use

For the quantitative in vitro determination of Alanine Aminotransferase (ALT) in serum. This product is suitable for Manual use.

Clinical Significance

Alanine Aminotransferase is one of the enzymes within the aminotransferases group and are among the most sensitive liver enzymes. The highest concentrations of the ALT enzyme can be in the liver, with decreasing concentrations found in the kidneys, heart, skeletal muscle, pancreas, spleen and lung tissue respectively.

ALT measurements are used in the diagnosis of hepatic damage and diseases including viral hepatitis and cirrhosis.

The normal concentration levels of ALT in the blood are low, however, when damaged, the liver releases more ALT into the blood causing the concentration levels to rise. When diagnosing for hepatic damage, the root cause of the damage can be established, such as disease, drug, or injury.

The ALT test not only allows for the diagnosis of liver disease but also allows for the diagnosis of the root cause of the disease.

It is often tested in combination with the aspartate aminotransferase (AST) test as part of the hepatic panel with alanine aminotransferase levels being higher in most types of liver disease.

Principle

Alanine Aminotransferase is measured by monitoring the concentration of pyruvate hydrazone formed with 2,4-dinitrophenylhydrazine.

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