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ASO (complete kit with glass slides) assay

Product Method Size Catalog Price Quantity
ASO (complete kit with glass slides) assay Latex Slide Test 100T LO2715 $260.35
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  • Assay Range
    Sensitivity approx 200lU/ml
  • Working Stability 2-8 °C
    Stable to expiry
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Intended Use

Latex agglutination slide test for the qualitative and semi-quantitative determination of Anti-Streptolysin O (ASO) in human serum. Detection of ASO in serum may aid in the diagnosis of streptococcal infections. This test kit is for in vitro diagnostic use only. This product is suitable for Manual use.

Clinical Significance

In those infections promoted by acute streptococcal infection, anti-streptolysin O antibodies are produced due to the presence of the streptolysin O antigen liberated by the bacteria. Information on the extent and degree of infection can be obtained from the measurement of serum ASO levels.

Increased ASO levels are also associated with rheumatic fever and glomerulonephritis.

Principle

The ASO reagent contains latex particles coated with streptolysin O antigen. When the reagent is mixed with serum containing ASO at a level greater than 200 IU/ml the particles will agglutinate. This is interpreted as being a positive sample.

For the semi-quantification of ASO the sample is diluted over a range of dilutions and each is tested qualitatively. The ASO level can be estimated from the last dilution with visible agglutination.