Home Reagents Clinical Chemistry Reagents CK-MB assay
Quality Guranteed Fast Delivery ad for support

CK-MB assay

Product Method Size Catalog Price Quantity
CK-MB assay Immunoinhibition 19 x 2.5ml CK1296 $273.16
Shipping costs will be added at the checkout stage, click here for charges.
  • Format
    Lyophilised
  • Assay Range
    23.5 - 2044 U/l
  • Working Stability 15-25 °C
    3 days
  • Working Stability 2-8 °C
    21 days
Request Kit Insert

Intended Use

For the quantitative in vitro determination of CK-MB in serum and plasma. This product is suitable for manual use and on the RX monza.

Clinical Significance

Creatine Kinase (CK) is internationally accepted as a sensitive and specific indicator of acute myocardial infarction (AMI). There are 3 iso-enzymes of CK, CK-MM, CK-MB and CK-BB. CK-BB is produced by the brain in very small insignificant amounts. CK-MM is produced by the skeletal and heart tissue and CK-MB is produced by the heart muscle. In the vast majority of cases the CK activity rises within 6 hours of an acute infarction. After about 20 hours maximum values are observed. The CK activity generally returns to normal between the fourth and fifth day post- infarction.

Principle

Immunoinhibition Assay: An antibody is incorporated in the CK reagent. This antibody will bind to and inhibit the activity of the M subunit of CK-MB. This means that only the activity of the B subunit in serum is measured. If the activity is multiplied by a factor of 2, it will give the activity of CK-MB in serum.

Available Applications

RX Monza