Home Reagents Cardiac Reagents CK-MB assay
Quality Guranteed Fast Delivery ad for support

CK-MB assay

Product Method Size Catalog Price Quantity
CK-MB assay Immunoinhibition R1 4 x 20ml, R2 4 x 6ml CK3813 $520.01
Shipping costs will be added at the checkout stage, click here for charges.
  • Format
    Lyophilised
  • Assay Range
    8.30 - 1182U/l
  • Working Stability 2-8 °C
    Stable to expiry
Request Kit Insert

Intended Use

A CK-MB test system is a device intended for the quantitative in vitro determination of CK-MB concentration in serum and plasma. This product is suitable for use on RX series instruments, which includes the RX daytona and the RX imola.

Clinical Significance

Creatine Kinase (CK) is internationally accepted as a sensitive and specific indicator of acute myocardial infarction (AMI). There are 3 iso-enzymes of CK, CK-MM, CK-MB and CK-BB. CK-BB is produced by the brain in very small insignificant amounts. CK-MM is produced by the skeletal and heart tissue and CK-MB is produced by the heart muscle. In the vast majority of cases the CK activity rises within 6 hours of an acute infarction. After about 20 hours maximum values are observed. The CK activity generally returns to normal between the fourth and fifth day post- infarction.

Principle

Immunoinhibition Assay: An antibody is incorporated in the CK reagent. This antibody will bind to and inhibit the activity of the M subunit of CK-MB. This means that only the activity of the B subunit in serum is measured. If the activity is multiplied by a factor of 2, it will give the activity of CK-MB in serum.

Available Applications

RX series instruments, including:

RX daytona

RX imola