Home Reagents Cardiac Reagents Ck-nac (liquid) (mono reagent) assay
Quality Guranteed Fast Delivery ad for support

Ck-nac (liquid) (mono reagent) assay

Product Method Size Catalog Price Quantity
Ck-nac (liquid) (mono reagent) assay IFCC 6x20.5ml CK3878 $399.70
Shipping costs will be added at the checkout stage, click here for charges.
  • Format
    Liquid
  • Assay Range
    19.4 - 2886U/L
  • Working Stability 15-25 °C
    _
  • Working Stability 2-8 °C
    7 days
Request Kit Insert

Intended Use

For the quantitative in vitro determination of Creatine Kinase in serum or plasma. This product is suitable for use on the RX Series instruments which includes the Rx Daytona and the Rx Imola.


Clinical Significance

Creatine Kinase (CK) is a dimeric enzyme that catalyzes the conversion of creatine to creatine phosphate, it is composed of two sub-units Muscle (M) and Brain (B) which associate to form three isoenzymes CK-MM, CK-MB and CK-BB. CK is present in many organs throughout the body but is perhaps found primarily in striated muscle, brain and heart tissues. Damage or disease to any of these tissues will result in elevated levels of the enzyme in the blood.

Determination of CK activity in both plasma and serum can therefore provide a sensitive and specific marker for myocardial infarction, hyperthyroidism, kidney disease, cerebrovascular accidents and skeletal muscle diseases such as muscular dystrophy.

The determination of CK using creatine phosphate and adenosine-5'-diphosphate (ADP) as substrates rather than creatine and adenosine-5'-triphosphate (ATP) has several advantages in test performance as it allows for a faster reaction rate resulting in greater sensitivity.


Principle

This method is an optimized standard method according to the concentrations recommended by the IFCC.