Description

Intended Use

For the quantitative in vitro determination of Complement C4 in serum. This product is suitable for automated, semi-automated and manual use.

Clinical Significance

Complement is a complex biological system which works in conjunction with antibody and other factors to protect the body from invasion by pathogens. When activated by either the classical or alternative pathway complement acts on biological membranes and may cause cell death. The human complement cascade consists of several distinct plasma proteins. Complement C4 levels are important in determining inherited or acquired deficiencies. Conversely, levels may rise in a variety of inflammatory and necrotic disorders as part of the acute-phase plasma protein response.

Available Applications

• Hitachi 917/Mod P
• RX modena