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CRP (Latex Test) (manual) assay

Product Method Size Catalog Price Quantity
CRP (Latex Test) (manual) assay Latex Slide Test 100T CP1423 $210.38
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  • Format
    Liquid ready-to-use
  • Assay Range
    Sensitivity approx 6mg/l
  • Working Stability 2-8 °C
    Stable to expiry
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Intended Use

Latex agglutination slide test for the qualitative and semi-quantitative in vitro determination of CRP in serum. This product is suitable for Manual use.

Clinical Significance

C-Reactive protein received its name in 1930 when Tillet and Francis discovered a protein in the serum of patients with pneumonia that formed a complex with the C-polysaccharide of pneumococcus. It is one of the proteins commonly referred to as acute phase reactants and provides a highly sensitive indicator of inflammatory conditions, infections and other disease states where tissue necrosis occurs.

Principle

The CRP reagent contains latex particles coated with Anti-Human CRP antibody. When the reagent is mixed with serum containing CRP at a level greater than 6 mg/l the particles will agglutinate. This is interpreted as being a positive sample.

The reagent may also be used for the semi-quantification of CRP. For this purpose, the sample is diluted over a range of dilutions and each is tested qualitatively. The CRP level can be estimated from the last dilution with visible agglutination.