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CRP (Full Range) assay

Product Method Size Catalog Price Quantity
CRP (Full Range) assay Latex Enhanced Immunoturbidimetric R1 2 x 13ml, R2 2 x 13ml CP8028 $542.64
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  • Format
    Liquid ready-to-use
  • Assay Range
    0.18 - 165mg/l
  • Working Stability 2-8 °C
    Stable to expiry
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Intended Use

A CRP test system is a device intended for the quantitative in vitro determination of C-reactive protein (CRP) concentration in serum or plasma. This product is suitable for use on RX series analyser RX modena.

Clinical Significance

C-reactive protein is present in serum of normal individuals at levels between 0 - 5 mg/l. Elevated levels outside the normal range are associated with acute phase response and measurements may be useful for the detection of infection, tissue injury, inflammatory disorders and associated diseases.

Research has indicated that CRP levels, which are within the normal range, can be used in a variety of different population subgroups for the assessment of cardiovascular risk for developing a fatal myocardial infarction. CRP levels within the normal range have been associated with coronary heart disease mortality in high-risk individuals. Elevated serum cholesterol levels, elevated diastolic blood pressure and cigarette smoking indicate high-risk.

A complete clinical history is required for accurate interpretation of CRP levels. CRP levels within the normal range may be affected by a number of different factors and should always be compared to previous values.

Principle

Sample is reacted with a buffer and anti-CRP coated latex. The formation of the antibody-antigen complex during the reaction results in an increase in turbidity, the extent of which is measured as the amount of light absorbed at 570 nm. By constructing a standard curve from the absorbance of the standards, CRP concentration of sample can be determined.

Available Applications

RX Modena

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