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Fructosamine assay

Product Method Size Catalog Price Quantity
Fructosamine assay Enzymatic R1 5 x 25ml, R2 5 x 6.3ml FR3133 $2331.22
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  • Assay Range
    Linear up to 1803umol/l
  • Working Stability 2-8 °C
    Stable to expiry
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Intended Use

Enzymatic assay for the quantitative in vitro determination of glycated protein (fructosamine) in human serum or plasma.

Clinical Significance

Diabetes mellitus is a disease associated with poor glycemic control. Numerous clinical studies, including the Diabetes Control and Complications Trial, have shown that diabetes related complications may be reduced by the long term monitoring and tight control of blood glucose levels.

In the diabetic patient where blood glucose levels are abnormally elevated the concentration of fructosamine also increases. The reason for this is that the fructosamine is formed by a non-enzymatic Maillard reaction between glucose and amino acid residues of proteins. During this glycation process, an intermediate labile Schiff base is produced which is converted to a more stable ketoamine (fructosamine) via an Amadori rearrangement.

The measurement of fructosamine is useful in monitoring the blood glucose level over the preceding 2-3 weeks. It is therefore a medium term indicator of diabetic control, whereas, the measurement of blood glucose is only a short term indicator.