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Valproic Acid assay

Product Method Size Catalog Price Quantity
Valproic Acid assay Latex Enhanced Immunoturbidimetric R1 2 x 12ml, R2 2 x 5ml TD3414 $842.42
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  • Format
    Liquid ready-to-use
  • Assay Range
    11.3 - 159ug/ml
  • Working Stability 2-8 °C
    Stable to expiry
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Intended Use

For the quantitative in vitro determination of Valproic Acid in human serum. This product is suitable for use on the RX series instruments which includes the RX daytona and RX imola.

Clinical Significance

Valproic acid is a widely used anti-epileptic drug. It is used in the treatment of primary and secondary generalized seizures. Valproic acid has also become increasingly effective in the control of partial seizures. Measurements obtained by this device are used in the diagnosis and treatment of valproic acid overdose and in monitoring levels of valproic acid to ensure appropriate therapy.

Principle

Randox Valproic Acid assay is a latex-enhanced immunoturbidimetric assay. It is based on the principle of measuring changes in scattered light. The latex particles are coated with valproic acid, which in the presence of valproic acid antibody solution, rapidly agglutinate.

When a sample containing valproic acid is introduced, the agglutination reaction is partially inhibited, slowing down the agglutination process. The rate of agglutination is inversely dependent upon the concentration of valproic acid in the sample. By monitoring the change in scattered light, as a change in absorbance, a concentration curve can be obtained. The actual change in absorbance is inversely proportional to the concentration of valproic acid in the sample.

This assay uses an end point method and multipoint calibration.

Available Applications

RX series instruments, including:

RX daytona

RX imola