Potassium assay
| Product | Method | Size | Catalog | Price | Quantity |
| Potassium assay | Enzymatic | R1 3 x 20ml, R2 3 x 9ml | PT3852 | £204.44 | |
| Shipping costs will be added at the checkout stage, click here for charges. | |||||
- Format
Lyophilised - Assay Range
2.46 - 11.2mmol/l - Working Stability 15-25 °C
_ - Working Stability 2-8 °C
7 days - Material Safety Data Sheets
Intended Use
For the quantitative in vitro determination of Potassium in Serum and Plasma. This application is suitable for use on the RX Series instruments which includes the Rx Daytona and Rx Imola.
Clinical significance
Potassium is an important mineral within the body often measured to monitor electrolyte balance and to help diagnose and treat disease conditions characterised by low or high blood potassium levels.
The most common cause of high potassium levels (Hyperkalaemia) is kidney disease however levels are also increased in diabetes, infection, Addison’s disease. Hyperkalaemia can also be a result of taking some drugs including anti inflammatory drugs and beta blockers.
Decreased levels of potassium in the blood (Hypokalaemia) are caused by excessive vomiting, diarrhoea or sweating and can indicate dehydration. In individuals with diabetes potassium levels may be low immediately after taking insulin, potassium levels are also low in people taking diuretics.
Potassium is extremely important to heart function and small changes in the levels of potassium in the blood can affect the activity of nerves and muscles with low levels being attributed to increased activity of heart muscle and high levels resulting in decreased muscle activity and increased risk of heart attack.
Principle
Potassium is determined enzymatically via Potassium-dependant pyruvate kinase activity using phosphoenolpyruvate as substrate. The pyruvate formed reacts with NADH in the presence of LDH to form Lactate and NAD. The corresponding decrease in absorbance at 340 nm is proportional to the potassium concentration.
- Various
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